VANAPALLI
LABORATORY
​PUBLICATIONS​
2022
92. Anjum, N., and Vanapalli, S. A.* Microfluidic emulsification with a surfactant and a particulate emulsifier: Dripping-to-jetting transitions and drop size scaling. Physics of Fluids, Accepted, 2022.
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91. Anupom, T., and Vanapalli, S.A.* A compact imaging platform for conducting C. elegans phenotypic assays on Earth and in spaceflight, Scientific Reports, Submitted, 2022.
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90. Soni. P., Anupom, T., Lesanpezeshki, L., Rahman. M., Hewitt, J., Vellone, M., Stodieck, L., Blawzdziewicz, J., Szewczyk, N. and Vanapalli, S.A.* Microfluidics-integrated space-flight hardware for measuring muscle strength of C. elegans across multiple generations on the International Space Station, Lab on Chip, Submitted, 2022.
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89. Moallem. G., Pore, A. A., Gangadhar, A., Sari-Sarraf, H.* and Vanapalli, S.A.* Detection of live breast cancer cells in brightfield microscopy images containing white blood cells by image analysis and deep learning. Journal of Biomedical Optics, Submitted, 2022.
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88. Hewitt, J.E., Laranjeiro, R., Norouzi, M., Ellwood, R., Antebi, A., Szewczyk, N.J., Driscoll, M. and Vanapalli, S.A.* Multi-environment phenotyping of C. elegans for robust evaluation of physical performance. Submitted, 2022.
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87. Norouzi, M., Singha S., Blawzdziewicz, J., Vanapalli, S. A., Vaughn, M. W*. Capillary imbibition of monodisperse emulsions in confined microfluidic channels. Soft Matter, Submitted, 2022.
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86. Surabhi S., Muto, K., Higashitani, N., Hashizume, T., Higashibata, A., Ellwood, R. A., Deane, C. S., Rahman, M., Vanapalli, S. A., Etheridge, T., Szewczyk, N. J., and Higashitani, A*. Loss of physical contact in space alters the dopamine system in C. elegans. iScience, 25, 103762, 2022. pdf
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85. Anjum, N., Chang, Y. W., and Vanapalli, S. A*. A nanonsheet-based combination emulsifier system for bulk-scale production of emulsions with elongated droplets and long-term stability. Colloids and Surfaces A. Physicochemical and Engineering Aspects, 640, 128403, 2022. pdf
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2021
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84. McIntyre, R.L., Denis, S.W., Kamble, R., Molenaars, M., Petr, M., Schomakers, B.V., Rahman, M., Gupta, S., Toth, M.L., Vanapalli, S.A., Jongejan, A., Scheibye-Knudsen, M., Houtkooper, R.H. and Janssens, G. E*. Inhibition of the neuromuscular acetylcholine receptor with atracurium activates FOXO/DAF-16-induced longevity. Aging Cell, 20: e13381, 2021. pdf
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83. McIntyre, R. L., Rahman, M., Vanapalli, S. A., Houtkooper, R. H., Janssens, G. E*. Biological age prediction from wearable movement data identifies nutritional and pharmacological interventions for healthy aging, Frontiers in Aging, 2, 2021. pdf
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82. Schiffer, I., Gerisch, B., Kazuto, K., Laboy, R., Hewitt, J., Denzel, M. S., Mori, M. A., Vanapalli, S. A., Shen, Y., Simmons, O., Antebi, A*. miR-1 coordinately regulates lysosomal v-ATPase and biogenesis to affect muscle contractility upon proteotoxic challenge during aging, eLife, 10, e66768, 2021. pdf
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81. Lesanpezeshki, L., Qadota, H., Norouzi, M., Kashyap, K., Lacerda C. M. R., Szewczyk, N.J., Benian, G. M. and Vanapalli, S. A*. Investigating the correlation of muscle function tests and sarcomere organization in C. elegans., Skeletal Muscle, 11, 20, 2021. pdf
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80. Laranjeiro, R., Harinath, G., Pollard, A.K., Gaffney, C.J., Deane, C.S., Vanapalli, S.A., Etheridge, T., Szewczyk, N.J. and Driscoll, M. Spaceflight Affects Neuronal Morphology and Alters Transcellular Degradation of Neuronal Debris in Adult Caenorhabditis elegans, iScience, 24, 2021. pdf
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79. Ellwood, R.A., Hewitt, J.E., Torregrossa, R., Etheridge, T., Piasecki, M., Vanapalli, S.A., Whiteman, M., Szewczyk, N.J. Hydrogen sulfide supplementation improves health in the C. elegans Duchenne muscular dystrophy model. PNAS, 118(9), 2021. pdf
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2020
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78. Land MH, Toth ML, MacNair L, Vanapalli SA, Lef-ever TW, Peters EN, Bonn-Miller MO. Effect of cannabidiol on the long-term toxicity and lifespan in the pre-clinical model Caenorhabditis elegans, Cannabis and Cannabinoid Research, 1–6, 2020. pdf
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77. Lakshmanan, H. H. S., Pore, A., Kohs, T. C. L., Yazar, F., Thompson, R. M., Jurney, P. L., Maddala, J., Olson, S. R., Shatzel, J. J., Vanapalli, S. A. and McCarty, O. J. T. Design of a microfluidic bleeding chip to evaluate antithrombotic agents for use in COVID-19 patients. Cellular and Molecular Bioengineering, 13(4), 331-339, 2020. pdf
76. Abedi, S., Chen, C. C. and Vanapalli, S. A. Catastrophic thermal destabilization of two-dimensional close-packed emulsions due to synchronous coalescence initiation. Soft Matter, 16, 6032-6037, 2020. pdf
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75. Jayarathne, S., Ramalingam, L., Edwards, H., Vanapalli, S. A. and Moustaid-Moussa, N. Tart cherry increases lifespan in Caenorhabditis elegans by altering metabolic signaling pathways. Nutrients, 12(5), 1482, 2020. pdf
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74. Rahman, M., Edwards, H., Birze, N., Gabrilska, R., Rumbaugh, K.P., Blawzdziewicz, J., Szewczyk, N.J., Driscoll, M. and Vanapalli, S.A. NemaLife chip: a micropillar-based microfluidic culture device optimized for aging studies in crawling C. elegans. Sci Rep 10, 16190, 2020. pdf
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73. Qadota, H., Moody, J. C., Lesanpezeshki, L., Moncrief, T., Kitzler, D., Bhat, P., Vanapalli, S. A., Oberhauser, A. F., Benian, G. M. A region of UNC-89 (obscurin) lying between two protein kinase domains is a highly elastic spring required for proper sarcomere assembly. Journal of Molecular Biology, 432, 17, 4799-4814, 2020. pdf
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72. Tang, Y. Q., Lee, S. A., Rahman, M., Vanapalli, S. A., Lu, H. and Schaefer, W. R. Ankyrins are intercellular tethers for TMC mechanotransduction channels. Neuron, 107, 112-125.e10, 2020. pdf
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71. Abedi, S., Chen, C. C. and Vanapalli, S. A. Collective nucleation dynamics in two-dimensional emulsions with hexagonal packing. Physical Review E, 101(3), 030602(R), 2020. pdf
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70. Pollard, A. K., Gaffney, C. J. , Deane, C. S., Balsamo, M., Cooke, M., Ellwood, R. A, Hewitt, J., Mierzwa, B., Mariani, A., Vanapalli, S. A., Etheridge, T. and Szewczyk, N. J. Molecular Muscle Experiment (MME): Hardware and operational lessons for future astrobiology space experiments. Astrobiology, 10, 1-9, 2020. pdf
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69. Gupta, S. and Vanapalli, S. A. Microfluidic shear rheology and wall-slip of viscoelastic fluids using holography-based flow kinematics. Physics of Fluids, 32, 012006, 2020. pdf
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2019
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68. Laranjeiro, R., Harinath, G., H., Hewitt, J. E., Hartman, J. H., Royal, M. A., Meyer, J. N., Vanapalli, S. A. and Driscoll, M. Swim exercise in C. elegans extends neuromuscular and intestinal healthspan, enhances learning ability, and protects against neurodegeneration. PNAS, 116, 23829, 2019. pdf
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67. Kamyabi, N., Huang, J., Lee, J. J., Bernard, V., Seeman, A., Stephens, B., Hurd, M. W., Vanapalli, S. A., Maitra, A. and Guerrero, P. A. A microfluidic device for label-free isolation of tumor cell clusters from unprocessed blood samples. Biomicrofluidics, 13, 044111, 2019. pdf
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66. Lesanpezeshki, L., Hewitt, J. E., Laranjeiro, R., Antebi, A., Driscoll, M., Szewczyk, N. J., Blawzdziewicz, J., Lacerda, C. M. R. and Vanapalli, S. A. Pluronic gel-based burrowing assay for rapid assessment of neuromuscular health in C. elegans. Scientific Reports, 9, 15246, 2019. pdf
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65. Vanapalli, S. A. How to tame a giant oscillation. Nature Physics, 15(7), 626-627, 2019. pdf
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64. Suteria, N. S., Gupta, S., Potineni, R., Baier, S. K., and Vanapalli, S. A. eCapillary: A disposable microfluidic extensional viscometer for weakly elastic polymeric fluids. Rheologica Acta, 58(6-7), 403-417, 2019. pdf
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63. Barakat, J. M., Ahmmed, S. M., Vanapalli, S. A. and Shaqfeh, E. S. G. Pressure-driven flow of a vesicle through a square microchannel. Journal of Fluid Mechanics. 861, 447-483, 2019. pdf
62. Abedi, S., Suteria, S. N., Chau-Chyun. C. and Vanapalli, S. A. Microfluidic production of size-tunable hexadecane-in-water emulsions: Effect of droplet size on destabilization of two-dimensional emulsions due to partial coalescence. Journal of Colloid and Interface Science, 533, 59-70, 2019. pdf
61. Pendyala, G., Bithi, S. S., Vanapalli, S. A. and Fernandez, G. Continuous and high throughput production of alginate fibers using co-flow in a millifluidic T-junction. Journal of Applied Polymer Science, 136, 47120, 2019. pdf
2018
60. Hewitt, J. E., Pollard, A. K., Lesanpezeshki, L., Deane, C. S., Gaffney, C. J., Etheridge, T., Szewczyk, N. S. and Vanapalli, S. A. Muscle strength deficiency and mitochondrial dysfunction in a muscular dystrophy model of Caenorhabditis elegans and its functional response to drugs. Disease Models and Mechanisms, 11, 12, 2018. pdf
59. C. J. Gaffney*, A. K. Pollard*, C. S. Deane, M.Cooke, M. Balsamo, J.Hewitt, S. A. Vanapalli, N. J. Szewczyk, T. Etheridge, B. E. Phillips. Worms in Space for Outreach on Earth: Space Life Science Activities for the Classroom. Gravitational and Space Research, 6, 2, 2018. pdf
58. Rahman, M., Hewitt, J. E., Van-Bussel, F., Hunter, E., Blawzdziewicz, J., Szewczyk, N. S., Driscoll, M. and Vanapalli, S. A. NemaFlex: A microfluidics-based technology for measurement of muscular strength of C.elegans. Lab on a Chip, 18, 2187-2120, 2018. pdf
57. Ahmmed, S. M., Bithi, S. S., Pore, A., Mubtasim, N., Schuster, C., Gollahon, L. and Vanapalli, S. A. Multi-sample deformability cytometry of cancer cells. APL Bioengineering, 2, 032002, 2018. pdf See also Scilight
56. Bilbao, A., Patel, A. K., Rahman, M., Vanapalli, S. A. and Blawzdziewicz, J. Roll maneuvers are essential for active reorientation of C.elegans in 3D media, PNAS, 115, E3616-E3625, 2018. pdf
55. Ahmmed, S.* M., Suteria, N. S.*, Garbin, V. and Vanapalli, S. A. Hydrodynamic mobility of confined polymeric particles, vesicles and cancer cells in a square microchannel. Biomicrofluidics, 12, 014114, 2018. pdf
54. Suteria, N., Nekouei, M. and Vanapalli, S. A. Microfluidic bypass manometry: Highly parallelized measurement of flow resistance of complex channel geometries and trapped droplets. Lab on a Chip, 18, 343-355, 2018. pdf
2017
53. Bouyanfif, A., Liyanage, S., Hewitt, J. E., Vanapalli, S. A., Moustaid-Moussa, N., Hequet, E., Abidi, N. FTIR imaging detects diet and genotype-dependent chemical composition changes in wild type and mutant C.elegans strains. Analyst, 142, 4727, 2017. pdf
52. Bithi, S. S.*, Nekouei, M.* and Vanapalli, S. A. Bistability in the hydrodynamic resistance of a drop trapped at a microcavity junction. Microfluidics and Nanofluidics, 21, 164, 2017. pdf
51. Kamyabi, N., Khan, Z. S. and Vanapalli, S. A. Flow-induced transport of tumor cells in a microfluidic capillary network - Role of friction and repeated deformation. Cellular and Molecular Bioengineering, 10, 563, 2017. pdf
50. Singh, D. K.*, Ahrens C. C.*, Li, W. and Vanapalli, S. A. Label-free high throughput holographic screening and enumeration of tumor cells in blood. Lab on a Chip, 17, 2920, 2017. pdf
49. Nekouei, M. and Vanapalli, S. A. Volume-of-fluid simulations in microfluidic T-junction devices: Influence of viscosity ratio on droplet size. Physics of Fluids, 29, 032007, 2017. pdf
48. Khan, Z. S., Kamyabi, N., Hussain, F., and Vanapalli, S. A. Passage times and friction due to flow of confined cancer cells and deformable particles through a microfluidic channel. Convergent Science Physical Oncology, 3, 024001, 2017. pdf
47. Singh, D. K., Ahrens C. C., Li, W. and Vanapalli, S. A. Label-free fingerprinting of tumor cells in bulk flow using inline digital holography microscopy. Biomedical Optics Express, 8, 536 - 554, 2017. pdf
46. Bithi, S. S and Vanapalli, S. A. Microfluidic cell isolation technology for drug testing of single tumor cells and their clusters. Scientific Reports, 7, 41707, 2017. pdf
2016
45. Wang, W. S. and Vanapalli, S. A. Mechanisms of mass transport during coalescence-induced microfluidic drop dilution. Physical Review Fluids, 1, 064001, 2016. pdf
44. Gupta, S., Wang, W. S. and Vanapalli, S. A. Microfluidic viscometers for shear rheology of complex fluids and biofluids. Biomicrofluidics, 10, 043402, 2016. (Special Topic: Microfluidic Rheology). pdf
43. Solomon, D. E., Raziq, A. and Vanapalli, S. A. A stress-controlled microfluidic shear viscometer based on smart-phone imaging. Rheologica Acta, 55(9), 727-738, 2016. pdf
42. Kamyabi, N. and Vanapalli, S. A. Microfluidic cell fragmentation for mechanical phenotyping of cancer cells. Biomicrofluidics,10, 021102, 2016. (Editor's Picks) pdf
2015
41. Bello, M. N., Pantoya, M. L., Kappagantula, K., Wang, W. S., Vanapalli, S. A., Irvin, D. J. and Wood, L. M. Reaction dynamics of rocket propellant with magnesium oxide nanoparticles. Energy & Fuels, 29, 6111-6117, 2015. pdf
40. Bithi, S. S and Vanapalli, S. A. Collective hydrodynamics of coalescing and non-coalescing drops in microfluidic parking networks. Soft Matter, 11, 5122-5132, 2015. pdf
39. Etheridge, T., Rahman, M., Gaffney, C. J., Shaw, D., Shepherd, F., Magudia, J., Solomon, D. E., Milne, T., Blawzdziewicz, J., Constantin-Teodosiu, D., Greenhalf, P. L., Vanapalli, S. A. and Szewczyk, N.J. The integrin-adhesome is required to maintain muscle structure, ATP production, and movement forces in Caenorhabditis elegans. FASEB Journal, 29, 1235-1246, 2015.pdf
2014
38. Wang, W. S. and Vanapalli, S.A. Millifluidics as a simple tool to optimize droplet networks: Case study on drop traffic in a bifurcated loop. Biomicrofluidics, 8, 064111, 2014. pdf
37. Bhattacharjee, B. and Vanapalli, S. A. Electrocoalescence based serial dilution of microfluidic droplets, Biomicrofluidics, 8, 044111, 2014. pdf
36. Maddala, J., Vanapalli, S. A. and Rengaswamy, R. Origin of periodic and chaotic dynamics due to drops moving in a microfluidic loop device. Physical Review E, 89, 023015. 2014. pdf
35. Bithi, S. S, Wang, W. S., Sun, M., Blawzdziewicz, J. and Vanapalli, S. A. Coalescing drops in microfluidic parking networks: A multifunctional platform for drop-based microfluidics. Biomicrofluidics. 8, 034118, 2014. pdf
34. Solomon, D. E. and Vanapalli, S. A. Multiplexed microfluidic viscometry for high throughput complex fluid rheology. Microfluidics and Nanofluidics. 16, 677-690, 2014. pdf
2013
33. Kim, J. and Vanapalli, S. A. Microfluidic production of spherical and non-spherical fat particles by thermal quenching of crystallizable oils. Langmuir. 29, 12307-12316, 2013. pdf
32. Bilbao, A., Wajnryb, E., Vanapalli, S. A. and Blawzdziewicz, J. Nematode locomotion in unconfined and confined fluids. Physics of Fluids, 25, 081902, 2013. (AIP News Release) pdf
31. Sun, M. and Vanapalli, S. A. Generation of chemical concentration gradients in mobile droplet arrays via fragmentation of long immiscible diluting plugs. Analytical Chemistry, 85, 2044-2048, 2013. pdf
30. Khan, Z. S. and Vanapalli, S. A. Probing the mechanical properties of brain cancer cells using a microfluidic cell squeezer device. Biomicrofluidics, 7, 011806, 2013. (Special Topic: Microfluidics in Cancer Research). pdf
29. Maddala, J., Wang, W. S., Vanapalli, S.A. and Rengasamy, R. Traffic of pairs of drops in microfluidic ladder networks with fore-aft structural asymmetry. Microfluidics and Nanofluidics, 14, 337-344, 2013. pdf
2012
28. Sun, M., Khan, Z. S. and Vanapalli, S. A. Blood plasma separation in a long two-phase plug flowing through disposable tubing. Lab on Chip, 12, 5225-5230, 2012. pdf
27. Padmanabhan, V., Khan, Z. S., Solomon, D. E., Armstrong, A., Rumbaugh, K., Vanapalli, S. A. and Blawzdziewicz, J. Locomotion of C. elegans: A piece-wise harmonic curvature-representation of nematode behavior. PLoS One, 7, e40121, 2012. pdf
26. Dewan, A., Jihye, K., McLean R. H., Vanapalli, S.A. and Karim, M. N. Growth kinetics of microalgae in microfluidic static droplet arrays. Biotechnology & Bioengineering, 109, 2987-2996, 2012. pdf
25. Chen, H., Lentz, D. M., Rhoades, A. M., Pyles, R. A., Haider, K. W., Vanapalli, S. A., Nunley, R. K. and Hedden, R. C. Surface infusion micropatterning of elastomeric substrates. Microfluidics and Nanofluidics, 12, 451-464, 2012. pdf
2011
24. Sun, M., Bithi, S. S. and Vanapalli, S. A. Microfluidic static droplet arrays with tuneable gradients in material composition. Lab on a Chip, 11, 3949-3952, 2011. (Cover Article) pdf
23. Maddala. J, Srinivasan, B., Bithi, S. S., Vanapalli, S. A. and Rengasamy, R. Design of a model-based feedback controller for active sorting and synchronization of droplets in a microfluidic loop. AIChE J, 58, 2120-2130, 2011. pdf
2010
22. Bithi, S. S. and Vanapalli, S. A. Behavior of a train of droplets in a fluidic network with hydrodynamic traps. Biomicrofluidics, 4, 044110, 2010. (Research Highlight). pdf
2000 - 2009
21. Vanapalli, S. A., Duits, M. H. G. and Mugele, F. Microfluidics as a functional tool for cell mechanics. Biomicrofluidics, 3, 012006, 2009. pdf
20. Li, Y., Vanapalli, S. A., Duits, M. H. G. Dynamics of ballistically injected latex particles in living human endothelial cells. Biorheology, 46, 309-321, 2009.
19. Vanapalli, S. A., Li, Y., Mugele, F. and Duits, M. H. G. On the origins of the universal diffusive dynamics of endogenous granules in mammalian cells. Molecular and Cellular Biomechanics, 150, 1-16, 2009.
18. Duits, M. H. G., Li, Y. Vanapalli, S. A., Mugele, F. Mapping of spatiotemporal heterogeneous particle dynamics in living cells. Physical Review E , 79, 051910, 2009.
17. Vanapalli, S. A., Wijnperle, D., van den Berg, A., Mugele, F. and Duits, M. H. G. Microfluidic valves with integrated structured elastomeric membranes for reversible fluidic entrapment and channel functionalization. Lab on a Chip, 9, 1461-1467, 2009.
16. Vanapalli, S. A., Banpurkar, A. G., van den Ende, D., Duits, M. H. G. and Mugele, F. Hydrodynamic resistance of single confined moving droplets in rectangular microchannels. Lab on a Chip, 9, 982-990, 2009.
15. Winkel, E. S., Oweis, G., Vanapalli, S. A., Perlin, M., Dowling, D. R., Solomon, M. J. and Ceccio, S. L. High Reynolds number turbulent boundary layer friction drag reduction from wall-injected polymer solutions. Journal of Fluid Mechanics, 621, 259-288, 2009.
14. Purnomo, E. H., van den Ende, D., Vanapalli, S. A. and Mugele. F. Glass transition and aging in dense thermosensitive suspensions of microgel particles. Physical Review Letters, 101, 238301, 2008.
13. Gu, H., Malloggi, F., Vanapalli, S. A. and Mugele, F. Electrowetting-enhanced microfluidic device for drop generation. Applied Physics Letters, 93, 183507, 2008.
12. Vanapalli, S. A., Iacovella, C. R., Sung, K. E., Mukhija, D., Mirecki-Millunchick, J., Burns, M. A., Glotzer, S. C. and Solomon, M. J. Fluidic assembly and packing of microspheres in confined channels. Langmuir, 24, 3661-3670, 2008.
11. Sung, K. E., Vanapalli, S. A., Mukhija, D., McKay, H., Mirecki-Millunchick, J., Burns, M. A. and Solomon, M. J. Programmable fluidic production of microparticles with configurable anisotropy. Journal of American Chemical Society, 130, 1335-1340, 2008.
10. Malloggi, F., Gu, H., Banpurkar, A. G., Vanapalli, S. A. and Mugele, F. Electrowetting- A versatile tool for microdrop generation. European Physical Journal E – Soft Matter, 26, 91-96, 2008.
9. Malloggi, F., Vanapalli, S. A., Gu, H. and Mugele, F. Electrowetting-controlled droplet generation in a microfluidic flow-focusing device. Journal Physics: Condensed Matter,19, 462101, 2007.
8. Vanapalli, S. A., van den Ende, D., Duits, M. H. G. and Mugele, F. Scaling of interface displacement in a microfluidic comparator. Applied Physics Letters, 90, 114109, 2007.
7. Vanapalli, S. A., Ceccio, S. L. and Solomon M. J. Universal scaling for polymer chain scission in turbulence. Proceedings of the National Academy of Sciences USA, 103, 16660-16665, 2006 (Editorial Highlight).
6. Vanapalli, S. A., Islam, M. T. and Solomon M. J. Scission-induced bounds on maximum polymer drag reduction in turbulent flows. Physics of Fluids, 17, 095108, 2005.
5. Islam, M. T., Vanapalli, S.A. and Solomon M. J. Inertial effects on polymer chain scission in planar elongational cross-slot flow. Macromolecules, 37, 1023-1030, 2004.
4. Vanapalli, S. A., Palanuwech, J. and Coupland, J. N. Stability of emulsions to dispersed phase crystallization-effect of oil type, dispersed phase volume fraction and cooling rate. Colloids & Surfaces A: Physicochemcial and Engineering Aspects, 204, 227-237, 2002.
3. Vanapalli, S. A., Palanuwech, J. and Coupland, J. N. Influence of fat crystallization on the stability of flocculated emulsions. Joural of Agriculture and Food Chemistry, 50, 5224-5228, 2002.
2. Vanapalli, S. A. and Coupland, J. N. Emulsions under shear – formation of partially coalesced lipid structures. Food Hydrocolloids,15, 507-512, 2001.
1. Vanapalli, S.A. and Coupland, J.N. Characterization of food colloids by phase analysis light scattering. Food Hydrocolloids, 14, 315-317, 2000.